靶点GPCR性药物找到 Targeted GPCR Drug Discovery
靶向中药GPCR中药看见
GPCR简单介绍 GPCR(G球蛋白偶连多巴胺感觉)是中成药剂量产品研发领域的大牌明星靶标，当今有超700种将建中成药剂量靶向治疗GPCR，约占当今很多将建中成药剂量的1/3GPCR在走势转导中更好地发挥着管理的本质用:癌症晚期、心肌病、痛风、阿尔茨海默病等损害社会建康的重大安全事故症状均与GPCR增进为重要性。可是，在GPCR家族性的的800众多GPCR会员中，必须大概90个是已发现的中成药剂量靶点，涵盖流浪儿童多巴胺感觉内的近300个会员在仿制药開發角度有为重要的使用价值与实力。
01
GPCR蛋白酶理解纯化 九游中心我的生命用顶尖的资产重组核淀粉酶实用功能性表示和纯化技术应用，在虫类和乳期昆虫受损细胞表示操作系统方便掌握了丰富多彩的技术，就能制得高几丁质酶、高纯净度的性药物靶点(GPCR核淀粉酶)，采用上下游实用功能性鉴定结论、机构介绍等个性化服务质量。
02
系统设计速冻电镜的GPCR结构设计解释 九游中心生命值依托于世界里出众的微冻电子设备体视显微镜系统，解析GPCR与治疗食用的用药获选原子核和好物的满辨别好坏率设备构造，为在下游AI治疗食用的用药挑选和针对设备构造的治疗食用的用药原子核看到出示多种且的关键的设备构造生态学学资料。
03
靶向口服药GPCR的納米免疫抗体口服药找到 九游中心寿命得到早熟的nm表面抗原口服药感觉品台和羊驼家庭养殖机地，会令用天然的库或免疫力库建立可以转换GPCR靶点活性氧的新实用功能nm表面抗原侯选口服药。
九游中心一生各项电子助力靶向疗法GPCR的药物研发部门 九游中心寿命以世界里领先地位的微米免疫免疫抗体知道网络游戏平台为根本，结合实际确定菌物工程学、的结构的菌物工程学和原子临床药理学等科技前沿科技水平，新创建了靶点GPCR的抗癫痫药物知道网络游戏平台，并非常重视于提供数据高的靶点GPCR微米免疫免疫抗体挑选等CRO工作，为GPCR的结构的解密及抗癌药物产品开发再添机械助力。
  • 给出一坐式高亲水性GPCR表达方法、纯化及结构类型技术鉴定的服务
  • GPCR功能表查验售后服务
  • 冷藏电镜重心
  • 为GPCR设备构造的抗癫痫药物找到
  • 人们将在内容的某一价段转换成内容施工进度行业报告
GPCR淀粉酶物品目录
Class A GPCR (Rhodopsin-like family)
Receptor Receptor family Species Expression system Description
0PRM1 opioid receptor human HEK293/Sf9 full length
0PRL1 opioid receptor human HEK293/Sf9 full length
0PRK1 opioid receptor human HEK293/Sf9 full length
0PRD1 opioid receptor human HEK293/Sf9 full length
CCR2 Chemokine Receptor human HEK293/Sf9 full length
CCR4 Chemokine Receptor human HEK293/Sf9 full length
CCR5 Chemokine Receptor human HEK293/Sf9 full length
CCR6 Chemokine Receptor human HEK293/Sf9 full length
CCR7 Chemokine Receptor human HEK293/Sf9 full length
CCR9 Chemokine Receptor human HEK293/Sf9 full length
Class A GPCR (Rhodopsin-like family)
Receptor Receptor family Species Expression system Description
V2R Vasopressin receptor human HEK293/Sf9 full length
5-HT 1A Serotonin receptor human HEK293/5f9 full length
5-HT1B Serotonin receptor human HEK293/Sf9 full length
MTR1A Melatonin receptor human HEK293/Sf9 full length
MTR1B Melatonin receptor human HEK293/Sf9 full length
ADAZA Adrenergic receptol human HEK293/5f9 full length
ADA2B Adrenergic receptol human HEK293/Sf9 full length
ADA2C Adrenergic receptol human HEK293/5f9 full length
ADRB1 Adrenergic receptol human HEK293/Sf9 full length
ADRB2 Adrenergic receptol human HEK293/Sf9 full length
Class A GPCR (Rhodopsin-like family)
Receptor Receptor family Species Expression system Description
CXCR1 Chemokine Receptor human HEK293/Sf9 full length
CXCR2 Chemokine Receptor human HEK293/5f9 full length
CXCR3 Chemokine Receptor human HEK293/Sf9 full length
CXCR4 Chemokine Receptor human HEK293/5f9 full length
CXCR5 Chemokine Receptor human HEK293/Sf9 full length
DRD1 Dopamine receptor human HEK293/Sf9 full length
DRD2 Dopamine receptor human HEK293/Sf9 full length
DRD3 Dopamine receptor human HEK293/5f9 full length
MC3R Melanocortin receptor human HEK293/Sf9 full length
MC4R Melanocortin receptor human HEK293/Sf9 full length
Class A GPCR (Rhodopsin-like family)
Receptor Receptor family Species Expression system Description
OXTR Oxytocin receptor human HEK293/Sf9 full length
GHSR Ghrelin receptor human HEK293/Sf9 full length
CB1 Cannabinoid receptor human HEK293/Sf9 full length
CB2 Cannabinoid receptor human HEK293/Sf9 full length
CCKAR Cholecystokinin receptor human HEK293/Sf9 full length
CCKBR Cholecystokinin receptor human HEK293/Sf9 full length
0X1R Orexin receptor human HEK293/Sf9 full length
0X2R Orexin receptor human HEK293/Sf9 full length
PTGDR2 prostaglandin receptor human HEK293/Sf9 full length
PTGDR3 prostaglandin receptor human HEK293/Sf9 full length
PTGDR4 prostaglandin receptor human HEK293/Sf9 full length
Class B GPCR (Rhodopsin-like family)
Receptor Receptor family Species Expression system Description
VIP2R Vasoactive intestinal polypeptide rece ptor human HEK293/Sf9 full length
VIP1R Vasoactive intestinal polypeptide rece ptor human HEK293/Sf9 full length
AMY3R Amylin receptor human HEK293/Sf9 full length
AMY2R Amylin receptor human HEK293/Sf9 full length
AMY1R Amylin receptor human HEK293/Sf9 full length
CRF2R Corticotropinreleasing hormone receptor human HEK293/Sf9 full length
CRF1R Corticotropinreleasing hormone receptor human HEK293/Sf9 full length
AM2R Adrenomedullin receptor human HEK293/Sf9 full length
AMIR Adrenomedullin receptor human HEK293/Sf9 full length
PTH2R Parathyroid hormone receptor human HEK293/Sf9 full length
Class B GPCR (Rhodopsin-like family)
Receptor Receptor family Species Expression system Description
PTH1R Parathyroid hormone receptor human HEK293/Sf9 full length
CRHR2 Corticotropin releasing hormone rece ptor human HEK293/Sf9 full length
CRHR1 Corticotropin releasing hormone rece ptor human HEK293/Sf9 full length
CALCR Calcitonin receptor human HEK293/Sf9 full length
GHRHR Glucagon receptor human HEK293/Sf9 full length
GIPR Glucagon receptor human HEK293/Sf9
GLP2R Glucagon receptor human HEK293/Sf9 full length
GLP1R Glucagon receptor human HEK293/Sf9 full length
GCGR Glucagon receptor human HEK293/Sf9 full length
SCTR Secretin receptor human HEK293/Sf9 full length
Class C GPCR (Rhodopsin-like family)
Receptor Receptor family Species Expression system Description
CASR Calcium-sensing receptor human HEK293/Sf9 full length
GPRC6A opioid receptor human HEK293/Sf9 full length
GPRC5D Glucagon receptor human HEK293/Sf9 full length
GPRC5C Chemokine Receptor human HEK293/Sf9 full length
GPRC5B Glucagon receptor human HEK293/Sf9 full length
GPRC5A Glucagon receptor human HEK293/Sf9 full length
GPR179 opioid receptor human HEK293/Sf9 full length
GPR158 opioid receptor human HEK293/Sf9 full length
GPR156 opioid receptor human HEK293/Sf9 full length
TAS1R3 Taste receptor human HEK293/Sf9 full length
TAS1R2 Taste receptor human HEK293/Sf9 full length
Class C GPCR (Rhodopsin-like family)
Receptor Receptor family Species Expression system Description
TAS1R1 Taste receptor human HEK293/Sf9 full length
mGluR7 Metabotropic glutamate receptor human HEK293/Sf9 full length
mGluR6 Metabotropic glutamate receptor human HEK293/Sf9 full length
mGluR5 Metabotropic glutamate receptor human HEK293/Sf9 full length
mGluR4 Metabotropic glutamate receptor human HEK293/Sf9 full length
mGluR3 Metabotropic glutamate receptor human HEK293/Sf9 full length
mGluR2 Metabotropic glutamate receptor human HEK293/Sf9 full length
mGluRI Metabotropic glutamate receptor human HEK293/Sf9 full length
GABBR2 Gamma-aminobutyric acid receptor human HEK293/Sf9 full length
GABBR1 Gamma-aminobutyric acid receptor human HEK293/Sf9 full length
CASR Calcium-sensing receptor human HEK293/Sf9 full length
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